G3902

Sigma

 

Ghrelin human

lyophilized powder

Amino Acid Sequence:Gly-Ser-Ser(O-n-octanoyl)-Phe-Leu-Ser-Pro-Glu-His-Gln-Arg-Val-Gln-Gln-Arg-Lys-Glu-Ser-Lys-Lys-Pro-Pro-Ala-Lys-Leu-Gln-Pro-Arg
MDL number:MFCD02687544

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Description

Biochem/physiol ActionsEndogenous ligand to the orphan growth-hormone secretagogue receptor that stimulates the release of growth hormone from the pituitary.
Physical formLyophilized from 0.1% aqueous TFA

Properties

formlyophilized powder
color white
solubility1% acetic acid: 1 mg/mL
Gene Informationhuman ... GHRL(51738)
storage temp.−20°C

References

referenceKamegai, J., et al., Central effect of ghrelin, an endogenous growth hormone secretagogue, on hypothalamic peptide gene expression. Endocrinology 141, 4797-4800, (2000)
 Wren, A.M., et al., The novel hypothalamic peptide ghrelin stimulates food intake and growth hormone secretion. Endocrinology 141, 4325-4328, (2000)
 Date, Y., et al., Ghrelin, a novel growth hormone-releasing acylated peptide, is synthesized in a distinct endocrine cell type in the gastrointestinal tracts of rats and humans. Endocrinology 141, 4255-4261, (2000)
 Seoane, L.M., et al., Ghrelin elicits a marked stimulatory effect on GH secretion in freely-moving rats. Eur. J. Endocrinol. 143, R007-R009, (2000)